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Survey of phytochemical composition and biological effects of three extracts from a wild plant (Cotoneaster nummularia Fisch. et Mey.): A potential source for functional food ingredients and drug formulations
Scopus
Open Access Toplam 120 atıf DOI
This study was focused on the analysis of the phenolic content, antioxidant, antibacterial, anti-cholinesterase, anti-tyrosinase, anti-amylase and anti-glucosidase activity of three solvent extracts from Cotoneaster nummularia. Moreover, water extract was tested in terms of mutagenic/anti-mutagenic effects. The antioxidant activities of these extracts were evaluated by DPPH, ABTS, O2, metal chelating, phosphomolybdenum, b-carotene/linoleic acid, ferric and cupric reducing power assays. Enzyme inhibitory activities were also examined with colorimetric methods. Generally, methanol and water extracts exhibited excellent biological activities. These extracts were rich in phenolic and flavonoid content. Furthermore, Cotoneaster extracts indicated appreciable antibacterial properties against human pathogen strains. HPLC analysis showed that ferulic acid, chlorogenic acid, (-)-epicatechin and (+)-catechin were the major phenolics in extracts tested. These data offer that these extracts from C. nummularia may be considered as a potential source of biological agents for developing functional foods or drug formulations. Copyright:
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Chemical composition profile of the essential oil from hymenocrater bituminous and its health functionality
Scopus
Havuzumuzda Open Access 10 atıf almış
Hymenocrater species are important medicinal and food plants. The aim of this work was to evaluate the potential of Hymenocrater bituminous Fisch. & C. A. Mey. for the management of public health problems such as Alzheimer’s disease, obesity, diabetes mellitus, and skin diseases through inhibition of targeted enzymes. Essential oil composition, antioxidant activity, and the total bioactive contents of the plant were also determined. EO showed high α-glucosidase (40 mmol ACEs/g oil), α-amylase (9 mmol ACEs/g oil), acetylcholinesterase (3.8 mg GEs/g oil), butyrylcholinesterase (4.7 mg GEs/g oil), tyrosinase (45 mg KAEs/g oil), and lipase (1.5 mmol OEs/g oil) inhibitory activities. Methanolic extract exhibited strong antiradical (DPPH and ABTS) and reducing power (CUPRAC and FRAP) activities and high total phenolics content (120 mg GAEs/g extract). Gas chromatography/mass spectrometry analysis of EO showed the presence of α-pinene (18.2%), β-pinene (11.3%), trans-phytol (11.0%), and spathulenol (8.5%) as the major components. The results indicated that H. bituminous has promising potential for possible uses in food and pharmaceutical industries due to its valuable phytoconstituents and biological activities.
Atıf Yapan Makale Bilgileri
Kurumlar (5)
Biotechnology Research Center,Tabriz
Tabriz, Iran
Research Center for Pharmaceutical Nanotechnology
Tabriz, Iran
Selçuk Üniversitesi
Selçuklu, Turkey
Università degli Studi di Camerino
Camerino, Italy
Urmia University of Medical Sciences
Urmia, Iran