Kurumun Atıf Alan Makalesi
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Antimicrobial and antiviral effects of essential oils from selected Umbelliferae and Labiatae plants and individual essential oil components
Scopus
Open Access Toplam 159 atıf DOI
The essential oils obtained from Anethum graveolens, Foeniculum vulgare collected at fully-mature and flowering stages, Mentha piperita, Mentha spicata, Lavandula officinalis, Ocimum basilicum (green- and purpleleaf varieties), Origanum onites, O. vulgare, O. munitiflorum, O. majorana, Rosmarinus officinalis, Salvia officinalis, and Satureja cuneifolia, as well as the widely encountered components in essential oils (γ-terpinene, 4-allylanisole, (-)-carvone, dihydrocarvone, D-limonene, (-)-phencone, cuminyl alcohol, cuminyl aldehyde, cuminol, trans-anethole, camphene, isoborneol, (-)-borneol, L-bornyl acetate, 2-decanol, 2-heptanol, methylheptane, farnesol, nerol, isopulegol, citral, citronellal, citronellol, geraniol, geranyl ester, linalool, linalyl oxide, linalyl ester, α-pinene, β-pinene, piperitone, (-)-menthol, isomenthone, carvacrol, thymol, vanillin, and eugenol), were screened for their antiviral activity against Herpes simplex type-1 (HSV-1) and parainfluenza type-3 (PI-3). Cytotoxicity was expressed as cytopathogenic effect. Most of the oils and compounds displayed strong antiviral effects against HSV-1, ranging between 0.8 and 0.025 μg mL<sup>-1</sup>. However, the samples tested were less effective against PI-3, with results ranging between 1.6 and 0.2 μg mL<sup>-1</sup>. The essential oil of A. graveolens was the most active. Most of the tested oils and compounds exhibited good antibacterial and antifungal effects. © TÜBİTAK.
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In Vitro and in Vivo Biological Investigations of Camphene and Its Mechanism Insights: A Review
Scopus
Havuzumuzda 113 atıf almış
Camphene (C10H16) also-called2,2-dimethyl-3-methylidenebicyclo[2.2.1] heptane is a volatile compound belonging to the terpenoid family, in particular to the group of monoterpene hydrocarbons. It is presented as a secondary metabolite in various aromatic and medicinal plants, especially Thymus, Origanum, and Salvia genera, and is considered one of the major components of their essential oils. Numerous in vitro and in vivo investigations have proven the biological properties of camphene including antibacterial, antifungal, anticancer, antioxidant, antiparasitic, antidiabetic, anti-inflammatory, and hypolipidemic activities. Moreover, camphene was also reported to exhibit anti-leishmanial, hepatoprotective, antiviral, and anti-acetylcholinesterase inhibitory activities. The current review highlights the previous reports on the biological properties of this molecule; camphene. The mechanisms of action involved and the potential application of camphene as a drug are also discussed. In light of these findings, in-depth preclinical and clinical studies on this molecule are strongly required to validate its applications in pharmaceutical field. Presented information could shed light into further studies on this molecule.
Atıf Yapan Makale Bilgileri
Kurumlar (7)
Faculté de Médecine et de Pharmacie de Rabat
Rabat, Morocco
Faculté des Sciences Dhar El Mahraz, Université Sidi Mohamed Ben Abdellah
Fez, Morocco
Faculté des Sciences Rabat
Rabat, Morocco
Moscow State University of Technologies and Management
Moscow, Russian Federation
Selçuk Üniversitesi
Selçuklu, Turkey
Université Abdelmalek Essaadi
Tetouan, Morocco
Université Sidi Mohamed Ben Abdellah
Fez, Morocco