Changes in Serum Biochemical Values in Adult Cattle with Foot and Mouth Disease

The aim of this research was to determine the changes in serum biochemical values of adult cattle with foot and mouth disease (FMD). Blood samples were obtained from adult Holstein cattle with FMD (n=7) and healthy cattle (n=5, control). Serum was extracted from these, and cardiac, hepatic, and renal damage markers, as well as lipid metabolism products and phosphorous levels were measured. High-density lipoprotein levels were 97.5±23.6 mg/dL and 145.2±10.9 mg/dL in cattle with FMD and control animals, respectively, and these values were significantly different (P<0.001). Blood urea nitrogen levels were 26.5±8.28 mg/dL and 41.4±7.53 mg/dL in cattle with FMD and control animals, respectively, and these values were significantly different (P<0.05). In conclusion, it may be stated that FMD does not cause significant changes in cardiac, hepatic, or renal damage markers, or in lipid metabolism products or phosphorous levels in adult cattle, as the measured values were not significantly different from those of healthy cattle. These results may useful for the diagnosis of FMD, as well as for the evaluation of other laboratory findings.