Diagnostic value of fluorodeoxyglucose positron emission tomography-computed tomography in a patient with adrenal involvement of hodgkin lymphoma

Improved success with the modern management of Hodgkin lymphoma (HL) leaded new method searches to diminish treatment intensities in order to prevent late effects. Sensitivity and specificity of fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) is advanced in the determination of malign cell infiltrations in adrenal glands in patients with HL which is a rare finding. A 7.5 year old female patient that was investigated due to pubic hairs and breast development one year ago presented, with complaints of recently developed fever, asthenia, weight loss and night sweating. In her examination, hepatosplenomegaly, phase 2 pubarche and phase 1 thelarche were detected; in FDG PET-CT, advanced lymph node involvement and increased activity in spleen and left adrenal gland were also detected. The patient was diagnosed with HL by biopsy and premature pubarche (PP) by the laboratory values. In the patient, FDG PET-CT that is recorded after the antineoplastic treatment was completely normalized; pubarche and thelarche were completely rested and, normal puberty started when she was 12 years old. The patient has been followed up currently without any problems. In this report, a pediatric HL case with PP and increased activity in left adrenal gland determined by FDG PET-CT, has been presented.