Compared effects of surgical and natural menopause on climacteric symptoms, osteoporosis, and metabolic syndrome

Objective: To compare the effects of surgical (ie, earlier) and natural (ie, later) menopause on climacteric symptoms, osteoporosis, and metabolic syndrome. Method: The study was conducted with 94 women who underwent hysterectomy and bilateral oophorectomy and 95 women who were older than 40 years and in natural menopause. None had received hormone theraphy or osteoporosis treatment. Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment Panel III. Results: The rates of hot flushes (P = 0.001), sweating (P = 0.001), poor memory (P = 0.04), change in sexual desire (P = 0.04), and osteoprosis (diagnosed in the hip bone, P = 0.005) were significantly higher among the women in surgical menopause, but the rate of metabolic syndrome was similar in the 2 groups (47.8% and 40%; P = 0.28). Conclusion: Compared with natural menopause, surgical menopause was found to be associated with highter rates of climacteric symptoms and osteoporosis but not of of metabolic syndrome. Crown Copyright © 2009.