Intraperitoneal versus interpleural analgesia on post-operative pain to laparoscopic cholecystectomy

In our study, we aimed to compare the quality and duration of analgesia intrapleural bupivacaine, bupivacaine+morphine, only morphine and intraperitoneal bupivacaine, bupivacaine+morphine and only morphine administration for relieving pain after laparoscopic cholecystectomy. 90 cases of ASA I-II class were included in the study. Cases were randomly allocated in six groups. At the end of surgery, Group I (n=15) intraperitoneal 3 mg morphine in 30 mL saline; Group II (n=15) intraperitoneal 30 mL % 0.25 bupivacaine; Group III (n=15) intraperitoneal 30 mL % 0.25 bupivacaine+3 mg morphine; Group IV (n=15) interpleural 3 mg morphine in 30 mL saline; Group V (n=15) interpleural 30 mL % 0.25 bupivacaine; Group VI (n=15) interpleural 30 mL % 0.25 bupivacaine+3 mg morphine were administered. Postoperatif pain was assesed by a visual analog scale, numeric rating scale in 1,2,4,6,12, 24 hours and side effect were recorded for 24 hours. Interpleural bupivacaine was effective for postoperative pain relief and adding morphine to bupivacaine does not increase the quality and duration of analgesia. There were no differences in intraoperative fentanyl consumption and postoperative pain scores (NRS, VAS) were less in groups V and VI than groups I,II,III,IV.