Investigation of antioxidant and antibacterial activities of some hypericum species

The in vitro antioxidant and antibacterial activities of the methanol extracts of three Hypericum species (Hypericum aviculariifolium Jaub. & Spach subsp. depilatum (Freyn & Bornm.) Robson var. depilatum, Hypericum salsugineum Robson & Hub.-Mor., Hypericum perforatum L.) growing in Turkey were investigated. The antioxidant capacities of the extracts were evaluated by different assays, including total phenolic content, total flavonoid content, free radical scavenging activity (DPPH assay), total antioxidant activity by ß-carotene-linoleic acid assay, ferric and cupric reducing assay and metal chelating activity. Antibacterial activity was screened using a broth microdilution assay against a panel of standardized bacteria. Results showed that the methanolic extract of H. salsugineum showed the highest antioxidant activity among the extracts. Hypericum perforatum was the most effective extract among extracts of all Hypericum species tested and Listeria monocytogenes was the most sensitive bacterium against all extracts. © by PSP.