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Objectives: This study aimed to assess the impact of malnutrition on liver and spleen stiffness in children using shear wave elastography (SWE) and to compare the findings with those of healthy controls. Methods: A total of 308 children aged 0–18 years were prospectively enrolled and classified as either malnourished or healthy according to World Health Organization (WHO) growth reference standards (weight-for-height Z-scores for children under 5 years and BMI-for-age Z-scores for those aged 5 years and older). Liver and spleen stiffness measurements were obtained using SWE by a single pediatric radiologist blinded to nutritional status. Statistical comparisons were performed between groups, across malnutrition severity subgroups, and within different age categories. Results: Liver stiffness did not differ significantly between malnourished children overall and healthy controls, but it was markedly higher in those with severe malnutrition compared to mild or moderate cases (p = 0.018). Spleen stiffness was significantly lower in malnourished children aged 0–6 years compared to controls (p < 0.001). Both liver and spleen stiffness values increased with age (p = 0.014 and p = 0.013, respectively). Conclusion: Our findings indicate that malnutrition is associated with age- and severity-dependent alterations in liver and spleen stiffness. Liver stiffness was elevated only in children with severe malnutrition, whereas spleen stiffness was reduced in younger children but not in older ones. SWE may serve as a valuable non-invasive tool for assessing organ-level effects of malnutrition, and these results may guide future research on the reversibility and clinical significance of such changes. (Table presented.)
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Belge Türü
Kaynak: EUROPEAN JOURNAL OF PEDIATRICS
Anahtar Kelimeler (WoS)
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Scimago Dergi Bilgisi
Otomatik ISSN Eşleştirmesi
2025 yılı verileri
European Journal of Pediatrics
Q1
SJR Quartile
0,978
SJR Skoru
120
H-Index
Kategoriler: Pediatrics, Perinatology and Child Health (Q1)
Alanlar: Medicine
Ülke: Germany
· Springer Science and Business Media Deutschland GmbH
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Anahtar Kelimeler
WoS |
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Makale Bilgileri
Dergi
European Journal of Pediatrics
ISSN
0340-6199
Yıl
2025
/ 9. ay
Cilt / Sayı
184
Makale Türü
Özgün Makale
Hakemlik
Hakemli
Endeks
SCI-Expanded
JCR Quartile
Q1
Teşvik Puanı
0,56
· YÖKSİS Akademik Teşvik
Yayın Dili
Türkçe
Kapsam
Uluslararası
Toplam Yazar
8 kişi
Erişim Türü
Basılı+Elektronik
Alan
Sağlık Bilimleri Temel Alanı
Çocuk Gastroenterolojisi (Çocuk Sağlığı ve Hastalıkları)
YÖKSİS Yazar Kaydı
Yazar Adı
AĞIR MEHMET AKİF,ÖZTÜRK MEHMET,KÖREZ MUSLU KAZIM,GÜMÜŞ MELTEM,ABİDİN İLHAN,AYDIN VESİLE BETÜL,KELEŞ ALP ESMA,EMİROĞLU HALİL HALDUN
YÖKSİS ID
9036945