Objective: In this study, it is aimed to examine the compassion fatigue in anesthesia care providers based on the relationship between patients and anesthesia care providers. Materials and Method: The research was carried out with 185 anesthesia care providers working in 4 different university hospitals in 3 different provinces (Kocaeli, İzmir, Konya) located in 3 different regions (Marmara, Aegean, Central Anatolia) in Turkey. The data of the study were collected by the online survey technique prepared by the researcher using the Google forms application. Compassion Fatigue Short Scale (MYLS) developed by Adams et al. was used in the study. Results: As a result of the research, it is observed that the level of compassion fatigue of anesthesia care providers is moderate (67,24). In addition, a significant difference was found between the staff status of the participants, the status of being on duty, the province they worked in, the title and the number of weekly operations, and compassion fatigue. In terms of gender, a significant difference was obtained only with the secondary trauma dimension. Conclusion: As a result of the research, moderate compassion fatigue was found in anesthesia care providers. It is predicted that this level may decrease to better levels if necessary precautions are taken, otherwise the level will rise. It is thought that with the increase of compassion fatigue, both the delivery of health services and health professionals will be adversely affected. Therefore, it is necessary to pay due attention to the issue.