Traditional fire extinguishing methods can harm people and nature. For this purpose, in this study, no harmful acoustic-driven airflow fire extinguishing system was developed and experiments were carried out to extinguish gasoline, kerosene, thinner (synthetic thinner) liquid fuels and liquid petroleum gas (LPG) flames. 17,442 extinguishing experiments were conducted in 5 different flame sizes, 54 different frequencies and 10 cm to 190 cm distance range. The data obtained were analyzed using the polynomial regression method. For liquid fuels, the frequencies of 10 Hz to 50 Hz at a distance of 10 cm to 100 cm, 10 Hz to 32 Hz at a distance of 100 cm to 150 cm, and 10 Hz to 28 Hz at a distance of 150 cm to 180 cm are effective extinguishing ranges. LPG fuel, 10 Hz to 45 Hz at a distance of 10 cm to 140 cm, frequencies of 15 Hz to 30 Hz at a distance of 140 cm to 180 cm are effective extinguishing ranges. In addition, caused by the compression of the woofers membrane inside the collimator and the injected airflow at frequency of 30 Hz reduced the 12 cm diameter metal plate from 86.2°C to 18.8°C in 5 min, and the metal plate left to cool down from 80°C to 21.7°C in 10 min at a distance of 100 cm. The average Mean Square Error value obtained as a result of polynomial regression analysis is 0.9544, and the Root Mean Square Error value is 1.2020.