Herein, this study shows three different synthesis of gold nanoparticles with various nano-shapes and an investigation of the correlation between nano-shapes and electrochemical effects on dopamine oxidation. To synthesize nano-shaped gold nanoparticles green reducing sources such as rose extract, glucose, and pomegranate juice were used. Thereby, three different gold nanoparticles were synthesized. In order to examine nanoparticle shapes microscopic and spectroscopic characterizations of nanoparticles were carried out. Subsequently the effects of shapes on electrochemical probes and dopamine were accomplished. As a result, it was confirmed that the shapes of the same metal nanoparticles had different effects on electrochemical experiments.