Scopus Eşleşmesi Bulundu
21
Atıf
14
Cilt
521-526
Sayfa
🔓
Açık Erişim
Özet
Introduction: Thyroid dysfunction is among the most common autoimmune disorders in women of reproductive age. Previous studies have shown the association between autoimmune thyroid disease (AITD) and infertility. Anti-Müllerian hormone (AMH) is secreted by granulosa cells and is a useful marker for assessment of ovarian reserve. In the present study, we sought to evaluate the ovarian reserves of women with autoimmune thyroid disorder by measurement of AMH values. Material and methods: This prospective study included women with newly diagnosed AITD aged between 20 and 40 years. Patients were divided into three groups: Subclinical hypothyroidism (SCH, n = 21), overt hypothyroidism (OH, n = 21) and controls (CG, n = 32). Study parameters included serum free T4, free T3, thyroid-stimulating hormone, anti-thyroglobulin, anti-thyroid peroxidase antibodies, follicle-stimulating hormone, luteinizing hormone, estradiol and AMH concentrations measured in the early follicular phase. Antral follicle count (AFC) was assessed with ultrasound. Body mass index (BMI) and waist circumference of the patients were noted. Results: No significant difference was found among SCH, OH and CG in regard to ovarian reserves measured by AMH values (p = 0.19) and AFC (p = 0.80). A significant negative correlation was found between AMH and BMI (r = -0.382, p = 0.001). Anti-Müllerian hormone and waist circumference (r = -0.330, p = 0.004) were also negatively correlated. Conclusions: Although AMH values were not significantly different among groups, AMH values were lower in OH and SCH patients, indicating a possible need for close monitoring of these patients.
Web of Science Eşleşmesi Bulundu
19
WoS Atıf
14
Cilt
Article
Belge Türü
Kaynak: ARCHIVES OF MEDICAL SCIENCE
· s. 521-526
Anahtar Kelimeler (WoS)
Havuzumuzdaki Atıflar 0
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Anahtar Kelimeler
WoS |
Bir kelimeye tıklayıp ilgili kaynaktaki yayınları görün.
Makale Bilgileri
Dergi
Archives of Medical Science
ISSN
1734-1922
Yıl
2018
/ 1. ay
Cilt / Sayı
14
Makale Türü
Özgün Makale
Hakemlik
Hakemli
Endeks
SCI-Expanded
JCR Quartile
Q2
Teşvik Puanı
1,44
· YÖKSİS Akademik Teşvik
Yayın Dili
Türkçe
Kapsam
Uluslararası
Toplam Yazar
5 kişi
Erişim Türü
Elektronik
Alan
Sağlık Bilimleri Temel Alanı
TIP
YÖKSİS Yazar Kaydı
Yazar Adı
KÜÇÜKLER FERİT KERİM, GÖRKEM ÜMİT, ŞİMŞEK YASİN, KOCABAŞ RAMAZAN, GÜLER SERDAR
YÖKSİS ID
5289008