CANLI
Yükleniyor Veriler getiriliyor…
SCI Özgün Makale Scopus
The Impact of Early Versus Late Platelet and Neutrophil Recovery after Induction Chemotherapy on Survival Outcomes of Patients with Acute Myeloid Leukemia
Turkish Journal of Hematology 2020 Cilt 37 Sayı 2
Scopus Eşleşmesi Bulundu
13
Atıf
37
Cilt
116-120
Sayfa
🔓
Açık Erişim
Özet
Objective: The prognosis of patients with acute myeloid leukemia (AML) is affected by factors that are both patient-and diseasespecific. The aim of this study is to evaluate the impact of early versus late platelet and neutrophil recovery after induction chemotherapy on survival outcomes of AML patients. Materials and Methods: A total of 181 patients with AML who were treated in our tertiary center between 2001 and 2018 were evaluated. Neutrophil and platelet recovery times were accepted as the periods from the beginning of induction chemotherapy to a neutrophil count of ≥0.5x109/L and a platelet count of ≥20x109/L 3 days in a row, respectively. The median time to platelet recovery was 25 days (range=12-52) for all patients. Therefore, platelet recovery in the first 25 days was defined as early platelet recovery (EPR) and at ≥26 days it was defined as late platelet recovery (LPR). The median time to neutrophil recovery was 28 days (range=13-51) for all patients. Therefore, neutrophil recovery in the first 28 days was defined as early neutrophil recovery, and at ≥29 days it was defined as late neutrophil recovery. Results: The 5-year overall survival (OS) rates for patients who had EPR and LPR after induction chemotherapy were 62% and 23%, respectively (p<0.001). The 5-year disease-free survival (DFS) rates for patients who had EPR and LPR after induction chemotherapy were 57% and 15%, respectively (p<0.001). Conclusion: Short bone marrow recovery time may indicate better healthy hematopoiesis and marrow capacity associated with longer OS and DFS.
Web of Science Eşleşmesi Bulundu
14
WoS Atıf
37
Cilt
Article
Belge Türü
Kaynak: TURKISH JOURNAL OF HEMATOLOGY · s. 116-120
Anahtar Kelimeler (WoS)

Havuzumuzdaki Atıflar 0

Bu makaleye, sistemimizdeki Scopus veritabanında bulunan 0 makale atıf yapmıştır. Scopus genel atıf sayısı: 13.

Bu makaleye, kendi Scopus havuzumuzdaki başka bir makaleden atıf kaydı bulunmuyor.

Anahtar Kelimeler

WoS | Bir kelimeye tıklayıp ilgili kaynaktaki yayınları görün.

Makale Bilgileri

Dergi Turkish Journal of Hematology
ISSN 1308-5263 Archive Articles Aims and Scope Instructions For Authors Editorial Board Manuscript Submission Search Contact
Yıl 2020 / 1. ay
Cilt / Sayı 37 / 2
Sayfalar 116 – 120
Makale Türü Özgün Makale
Hakemlik Hakemli
Endeks SCI
Yayın Dili İngilizce
Kapsam Uluslararası
Toplam Yazar 9 kişi
Erişim Türü Elektronik
Alan Sağlık Bilimleri Temel Alanı TIP

YÖKSİS Yazar Kaydı

Yazar Adı ÇİFTÇİLER RAFİYE, HAZNEDAROĞLU İBRAHİM CELALETTİN, SAYINALP NİLGÜN, ÖZCEBE OSMAN İLHAMİ, AKSU SALİH, DEMİROĞLU HALUK, GÖKER HAKAN, MALKAN ÜMİT YAVUZ, BÜYÜKAŞIK YAHYA
YÖKSİS ID 5222248

Metrikler

Scopus Atıf 13
Havuz Atıfları 0
Yazar Sayısı 9