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20
Atıf
19
Cilt
🔓
Açık Erişim
Özet
Background: Attaining acceptable levels of LDL Cholesterol (LDL-C) significantly improves cardiovascular (CV) outcomes in patients with type 2 diabetes mellitus (T2DM). The LDL-C target attainment and the characteristics of patients attaining these targets were investigated in this study. Furthermore, the reasons for not choosing statins and the physicians’ attitudes on the treatment of diabetic dyslipidemia were also examined. Methods: A nationwide, cross-sectional survey was conducted in tertiary centers for diabetes management. Adult patients with T2DM, who were under follow-up for at least a year in outpatient clinics, were consecutively enrolled for the study. LDL-C goals were defined as below 70 mg/dL for patients with macrovascular complications or diabetic nephropathy, and below 100 mg/dL for other patients. Data about lipid-lowering medications were self-reported. Results: A total of 4504 patients (female: 58.6%) were enrolled for the study. The mean HbA1c and diabetes duration was 7.73 ± 1.74% and 10.9 ± 7.5 years, respectively. The need for statin treatment was 94.9% (n = 4262); however, only 42.4% (n = 1807) of these patients were under treatment, and only 24.8% (n = 448) of these patients achieved LDL-C targets. The main reason for statin discontinuation was negative media coverage (87.5%), while only a minority of patients (12.5%) mentioned side effects. Physicians initiated lipid-lowering therapy in only 20.3% of patients with high LDL-C levels. It was observed that the female gender was a significant independent predictor of not attaining LDL-C goals (OR: 0.70, 95% CI: 0.59–0.83). Conclusions: Less than 50 % of patients with T2DM who need statins were under treatment, and only a quarter of them attained their LDL-C targets. There exists a significant gap between the guideline recommendations and the real-world evidence in the treatment of dyslipidemia in T2DM.
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Makale Bilgileri
Dergi
Lipids in Health and Disease
ISSN
1476-511x
Yıl
2020
/ 11. ay
Cilt / Sayı
19
/ 237
Sayfalar
1 – 11
Makale Türü
Özgün Makale
Hakemlik
Hakemli
Endeks
SCI-Expanded
JCR Quartile
Q3
Teşvik Puanı
0,08
· YÖKSİS Akademik Teşvik
Yayın Dili
İngilizce
Kapsam
Uluslararası
Toplam Yazar
112 kişi
Erişim Türü
Elektronik
Alan
Sağlık Bilimleri Temel Alanı
Endokrinoloji ve Metabolizma Hastalıkları
YÖKSİS Yazar Kaydı
Yazar Adı
BAYRAM FAHRİ, SÖNMEZ YUSUF ALPER, Haymana Cem, SABUNCU TEVFİK, Dizdar Oğuzhan Sıtkı, GÜRKAN EREN, Kargılı Çarlıoğlu Ayşe, Ağbaht Kemal, ÖZDEMİR DİDEM, DEMİRCİ İBRAHİM, BARÇIN CEM, SALMAN SERPİL, TETİKER BEKİR TAMER, BALCI MUSTAFA KEMAL, KEBAPÇI MEDİNE NUR, ERSOY CANAN, YUMUK VOLKAN DEMİRHAN, Toth Peter P, SATMAN İLHAN, GÜLDİKEN SİBEL, AYTÜRK SALT SEMRA, Yılmaz Murat, Aşık Mehmet, DİNÇÇAĞ NEVİN, ÇAKMAK RAMAZAN, Türker Fulya, İdiz Cemile, Hacışahinoğulları Hülya, Bağdemir Elif, Yıldız Büşra, Haliloğlu Özlem, SANCAK SEDA, ÖZSARI LEVENT, Çağıltay Eylem, DEYNELİ OĞUZHAN, İmre Eren, GÖNEN MUSTAFA SAİT, Boysan Şerife Nur, ALTUNTAŞ YÜKSEL, Öztürk Feyza Yener, MERT MERAL, Pişkinpaşa Hamide, AYDIN HASAN, İmamoğlu Şazi, ÖZ GÜL ÖZEN, KÜÇÜKSARAÇ KIYICI DEVRİM SİNEM, Çetinarslan Berrin, SELEK ALEV, DOĞRU TEOMAN, KIRIK ALİ, EFE FATMA BELGİN, Kaya Ahmet, ÇORDAN İLKER, BALDANE SÜLEYMAN, KIRAÇ CEM ONUR, Capa Zehra, Cesur Mustafa, YETKİN İLHAN, ÇORAPÇIOĞLU DEMET, Canlar Şule, YILDIZ OKAN BÜLENT, Şendur Süleyman Nahit, ÇAKIR BEKİR, ÇORAKCI AHMET, Kutlu Mustafa, BAŞÇIL TÜTÜNCÜ NESLİHAN, BOZKUŞ YUSUF, ÇAKAL ERMAN, ÇARMIKLI DEMİRBAŞ BERRİN, ERTEK YALÇIN SİBEL, ALTAY MUSTAFA, Dağdeviren Murat, Abedi Amir Hassein, ÇETİNKALP ŞEVKİ, Özışık Hatice, Örük Güzide Gonca, YENER ABDULLAH SERKAN, Saydam Başak Özgen, GÜNEY ENGİN, ÜNÜBOL MUSTAFA, FİDAN YAYLALI GÜZİN, TOPSAKAL ŞENAY, HEKİMSOY ZELİHA, AKBABA GÜLHAN, ASLAN İBRAHİM, Dalkıran Şefika, AKBAY ESEN, GÜL KAMİLE, ÖZSAN YILMAZ MÜGE, Bozkırlı Emre, Çetinkaya Altuntaş Seher, ATMACA AYŞEGÜL, DURMUŞ ELİF TUTKU, METE TÜRKAN, KUTLUTÜRK FARUK, KÜÇÜKLER FERİT KERİM, DİKBAŞ OĞUZ, Akın Şafak, NUHOĞLU İRFAN, ERSÖZ HALİL ÖNDER, BAYRAKTAROĞLU TANER, Şişman Pınar, ŞAHİN İBRAHİM, Çetin Sedat, Çapoğlu İlyas, AKBAŞ EMİN MURAT, ÜÇLER RIFKI, EREN MEHMET ALİ, TUZCU ALPASLAN KEMAL, PEKKOLAY ZAFER, ÖZKAYA MESUT, ARAZ MUSTAFA
YÖKSİS ID
4995814