Scopus Eşleşmesi Bulundu
5
Atıf
19
Cilt
e205-e212
Sayfa
Özet
The aim of this study to impact of blood count recovery based complete remission before allogeneic hematopoietic stem cell transplantation (alloHSCT) on survival in patients with acute myeloid leukemia. We observed an equivalent post-transplant outcome between patients who were in complete remission and patients who were in complete response with incomplete blood count recovery before alloHSCT. We assume that alloHSCT eliminated the negative effect of pretransplant blood count levels. Background: Patients who achieve complete remission (CR) with incomplete blood count recovery (CRi) in acute myeloid leukemia (AML) have inferior overall survival and lower progression-free survival. The aim of this study was to define whether blood count recovery-based CR before allogeneic hematopoietic stem cell transplantation (alloHSCT) had an impact on survival in patients with AML. Materials and Methods: This study has been performed in a retrospective manner. One hundred one patients with AML who received an alloHSCT in our transplant center at Hacettepe University Hospital between the years 2001 and 2018 were evaluated. CRi were defined as bone marrow CR with absolute neutrophil count < 1000/mm3 and/or platelet count < 100.000/mm3. CR and CRi were confirmed just before alloHSCT in bone marrow and peripheral blood, respectively. Results: A total of 101 patients were entered into the study between 2001 and 2018. Median follow-up for all survivors was 38 months (range, 6-220 months). The 5-year overall survival for patients who were in CRi and patients who were in CR before transplantation were 58% and 67%, respectively (P = .68). The 5-year progression-free survival for patients who were in CRi and patients who were in CR before transplantation were 68% and 64%, respectively (P = .99). Conclusion: In conclusion, we observed equivalent posttransplant outcomes between patients who were in CR and patients who were in CRi before alloHSCT. We assume that alloHSCT eliminated the negative effect of pre-transplant blood count levels.
Web of Science Eşleşmesi Bulundu
5
WoS Atıf
19
Cilt
Article
Belge Türü
Kaynak: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
· s. E205-E212
Anahtar Kelimeler (WoS)
Havuzumuzdaki Atıflar 0
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Scimago Dergi Bilgisi
Otomatik ISSN Eşleştirmesi
2019 yılı verileri
Clinical Lymphoma, Myeloma and Leukemia
Q2
SJR Quartile
0,819
SJR Skoru
68
H-Index
Kategoriler: Hematology (Q2) · Cancer Research (Q3) · Oncology (Q3)
Alanlar: Biochemistry, Genetics and Molecular Biology · Medicine
Ülke: United States
· Elsevier Inc.
Bu bilgiler makale yılına göre Scimago veritabanından ISSN eşleştirmesiyle otomatik getirilmektedir.
Dergi sıralama verileri Scimago'nun ilgili yılı baz alınmaktadır.
Anahtar Kelimeler
Acute myeloid leukemia AlloHSCT Complete remission Incomplete remission
Acute myeloid leukemia
AlloHSCT
Complete remission
Incomplete remission
YÖKSİS WoS |
Bir kelimeye tıklayıp ilgili kaynaktaki yayınları görün.
Makale Bilgileri
Dergi
Clinical Lymphoma Myeloma and Leukemia
ISSN
2152-2650
Yıl
2019
/ 5. ay
Cilt / Sayı
19
/ 5
Sayfalar
205 – 212
Makale Türü
Özgün Makale
Hakemlik
Hakemli
Endeks
SCI-Expanded
Yayın Dili
İngilizce
Kapsam
Uluslararası
Toplam Yazar
5 kişi
Erişim Türü
Basılı+Elektronik
Alan
Sağlık Bilimleri Temel Alanı-
Hematoloji
YÖKSİS Yazar Kaydı
Yazar Adı
ÇİFTÇİLER RAFİYE,DEMİROĞLU HALUK,BÜYÜKAŞIK YAHYA,AKSU SALİH,GÖKER HAKAN
YÖKSİS ID
4544259