Scopus Eşleşmesi Bulundu
9
Atıf
19
Cilt
729-734
Sayfa
Özet
Background: The majority of patients with acute myeloid leukemia (AML) receive intensive induction chemotherapy for obtaining a complete remission (CR). Despite consolidation chemotherapy and advances in allogeneic hematopoietic stem cell transplantation, most of these patients finally relapse and die from AML. The aim of this study is to determine the impact of duration of remission achievement on survival of patients with newly diagnosed AML who achieve CR after induction chemotherapy. Materials and Methods: We retrospectively analyzed patients with AML who received first induction chemotherapy between 2001 and 2018. Results: The 5-year overall survival for patients who had early remission after induction chemotherapy and patients who had delayed remission after induction chemotherapy were 83% (95% confidence interval [CI], 0.79-0.87) and 35% (95% CI, 0.31-0.39), respectively (P <.001). The 5-year disease-free survival for patients who had early remission after induction chemotherapy and patients who had delayed remission after induction chemotherapy were 81% (95% CI, 0.75-0.87) and 28% (95% CI, 0.21-0.35), respectively (P <.001). Conclusion: In conclusion, time to entering CR is a predictor factor of overall survival and disease-free survival for patients with newly diagnosed AML who achieve CR after first induction chemotherapy. Patients achieving CR only after a lengthy time (eg, more than 29 days) should be considered to have high relapse rate and should undergo allogeneic hematopoietic stem cell transplantation. Most patients with acute myeloid leukemia (AML) receive intensive induction chemotherapy toward obtaining a complete remission. In this study, we evaluated whether the time from induction chemotherapy to complete remission in patients with AML affects survival outcomes. This study showed that the time between induction chemotherapy and complete remission in patients with AML was effective on survival outcomes.
Web of Science Eşleşmesi Bulundu
8
WoS Atıf
19
Cilt
Article
Belge Türü
Kaynak: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
· s. 729-734
Anahtar Kelimeler (WoS)
Havuzumuzdaki Atıflar 0
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Scimago Dergi Bilgisi
Otomatik ISSN Eşleştirmesi
2019 yılı verileri
Clinical Lymphoma, Myeloma and Leukemia
Q2
SJR Quartile
0,819
SJR Skoru
68
H-Index
Kategoriler: Hematology (Q2) · Cancer Research (Q3) · Oncology (Q3)
Alanlar: Biochemistry, Genetics and Molecular Biology · Medicine
Ülke: United States
· Elsevier Inc.
Bu bilgiler makale yılına göre Scimago veritabanından ISSN eşleştirmesiyle otomatik getirilmektedir.
Dergi sıralama verileri Scimago'nun ilgili yılı baz alınmaktadır.
Anahtar Kelimeler
YÖKSİS |
Bir kelimeye tıklayıp ilgili kaynaktaki yayınları görün.
Makale Bilgileri
Dergi
Clinical Lymphoma Myeloma and Leukemia
ISSN
2152-2650
Yıl
2019
/ 11. ay
Cilt / Sayı
19
/ 11
Sayfalar
729 – 734
Makale Türü
Özgün Makale
Hakemlik
Hakemli
Endeks
SCI-Expanded
Yayın Dili
İngilizce
Kapsam
Uluslararası
Toplam Yazar
9 kişi
Erişim Türü
Basılı+Elektronik
Alan
Sağlık Bilimleri Temel Alanı-
Hematoloji
YÖKSİS Yazar Kaydı
Yazar Adı
ÇİFTÇİLER RAFİYE,DEMİROĞLU HALUK,HAZNEDAROĞLU İBRAHİM CELALETTİN,SAYINALP NİLGÜN,AKSU SALİH,ÖZCEBE OSMAN İLHAMİ,GÖKER HAKAN,AYDIN MÜRÜVVET SEDA,BÜYÜKAŞIK YAHYA
YÖKSİS ID
4543837