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SCI-Expanded Özgün Makale Scopus
Impact of Time Between Induction Chemotherapy and Complete Remission on Survival Outcomes in Patients With Acute Myeloid Leukemia
Clinical Lymphoma Myeloma and Leukemia 2019 Cilt 19 Sayı 11
Scopus Eşleşmesi Bulundu
9
Atıf
19
Cilt
729-734
Sayfa
Özet
Background: The majority of patients with acute myeloid leukemia (AML) receive intensive induction chemotherapy for obtaining a complete remission (CR). Despite consolidation chemotherapy and advances in allogeneic hematopoietic stem cell transplantation, most of these patients finally relapse and die from AML. The aim of this study is to determine the impact of duration of remission achievement on survival of patients with newly diagnosed AML who achieve CR after induction chemotherapy. Materials and Methods: We retrospectively analyzed patients with AML who received first induction chemotherapy between 2001 and 2018. Results: The 5-year overall survival for patients who had early remission after induction chemotherapy and patients who had delayed remission after induction chemotherapy were 83% (95% confidence interval [CI], 0.79-0.87) and 35% (95% CI, 0.31-0.39), respectively (P <.001). The 5-year disease-free survival for patients who had early remission after induction chemotherapy and patients who had delayed remission after induction chemotherapy were 81% (95% CI, 0.75-0.87) and 28% (95% CI, 0.21-0.35), respectively (P <.001). Conclusion: In conclusion, time to entering CR is a predictor factor of overall survival and disease-free survival for patients with newly diagnosed AML who achieve CR after first induction chemotherapy. Patients achieving CR only after a lengthy time (eg, more than 29 days) should be considered to have high relapse rate and should undergo allogeneic hematopoietic stem cell transplantation. Most patients with acute myeloid leukemia (AML) receive intensive induction chemotherapy toward obtaining a complete remission. In this study, we evaluated whether the time from induction chemotherapy to complete remission in patients with AML affects survival outcomes. This study showed that the time between induction chemotherapy and complete remission in patients with AML was effective on survival outcomes.
Web of Science Eşleşmesi Bulundu
8
WoS Atıf
19
Cilt
Article
Belge Türü
Kaynak: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA · s. 729-734
Anahtar Kelimeler (WoS)

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Bu makaleye, sistemimizdeki Scopus veritabanında bulunan 0 makale atıf yapmıştır. Scopus genel atıf sayısı: 9.

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Scimago Dergi Bilgisi Otomatik ISSN Eşleştirmesi 2019 yılı verileri
Clinical Lymphoma, Myeloma and Leukemia
Q2
SJR Quartile
0,819
SJR Skoru
68
H-Index
Kategoriler: Hematology (Q2) · Cancer Research (Q3) · Oncology (Q3)
Alanlar: Biochemistry, Genetics and Molecular Biology · Medicine
Ülke: United States · Elsevier Inc.
Bu bilgiler makale yılına göre Scimago veritabanından ISSN eşleştirmesiyle otomatik getirilmektedir. Dergi sıralama verileri Scimago'nun ilgili yılı baz alınmaktadır.

Anahtar Kelimeler

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Makale Bilgileri

Dergi Clinical Lymphoma Myeloma and Leukemia
ISSN 2152-2650
Yıl 2019 / 11. ay
Cilt / Sayı 19 / 11
Sayfalar 729 – 734
Makale Türü Özgün Makale
Hakemlik Hakemli
Endeks SCI-Expanded
Yayın Dili İngilizce
Kapsam Uluslararası
Toplam Yazar 9 kişi
Erişim Türü Basılı+Elektronik
Alan Sağlık Bilimleri Temel Alanı- Hematoloji

YÖKSİS Yazar Kaydı

Yazar Adı ÇİFTÇİLER RAFİYE,DEMİROĞLU HALUK,HAZNEDAROĞLU İBRAHİM CELALETTİN,SAYINALP NİLGÜN,AKSU SALİH,ÖZCEBE OSMAN İLHAMİ,GÖKER HAKAN,AYDIN MÜRÜVVET SEDA,BÜYÜKAŞIK YAHYA
YÖKSİS ID 4543837

Metrikler

Scopus Atıf 9
Havuz Atıfları 0
Yazar Sayısı 9