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Whole-blood thrombelastography using calcium chloride activation in healthy cats
TURKISH JOURNAL OF VETERINARY ANIMAL SCIENCES 2013 Cilt 37 Sayı 1
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37
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68-75
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Özet
Thrombelastography (TEG, Haemoscope Corp., Niles, IL, USA) allows for a global evaluation of the hemostatic system; while conventional coagulation tests typically evaluate only one part of the coagulation system, TEG simultaneously examines the interaction between platelets, clotting factors, the fibrinolytic system, and clot retraction mechanisms. Since its development, TEG has been widely employed in human clinical medicine and research, but has only recently gained popularity in veterinary medicine. The purpose of this study was to establish TEG reference ranges in healthy cats using the citrated native technique. In this study, 31 clinically healthy cats were evaluated. We sampled healthy adult cats based on the absence of clinical signs of illness, normal physical examination findings, a complete blood count, hemostasis profile results, and no previous history of bleeding disorders. The cats had 2 distinct tracings: a "normal" tracing similar to that obtained in other species, and a "high lysis" tracing. The percent of lysis at 60 min (LY60) was significantly higher and the percent of lysis at 60 min after MA is reached (CL60) was significantly lower in the "high lysis" group (P < 0.001 for both). Cats in the "high lysis" group also had a significantly shorter reaction time (P = 0.02). Based on the results, citrated native TEG may provide valuable information on global hemostasis in cats. This technique has a high coefficient of variation for the reaction time, kinetic time, and LY60 parameters, likely due to platelet retraction. It should be useful for detecting hypo- and hypercoagulable states in cats with hemostatic disturbances. © TÜBİTAK.
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Kaynak: TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES · s. 68-75
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Scimago Dergi Bilgisi Otomatik ISSN Eşleştirmesi 2013 yılı verileri
Turkish Journal of Veterinary and Animal Sciences
Q3
SJR Quartile
0,218
SJR Skoru
44
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Kategoriler: Veterinary (miscellaneous) (Q3)
Alanlar: Veterinary
Ülke: Turkey · TUBITAK
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Makale Bilgileri

Dergi TURKISH JOURNAL OF VETERINARY ANIMAL SCIENCES
ISSN 1300-0128
Yıl 2013
Cilt / Sayı 37 / 1
Sayfalar 68 – 75
Makale Türü Özgün Makale
Hakemlik Hakemli
Endeks SCI-Expanded
Yayın Dili İngilizce
Kapsam Uluslararası
Toplam Yazar 6 kişi
Erişim Türü Basılı+Elektronik
Alan Sağlık Bilimleri Temel Alanı- Veterinerlik Fizyolojisi

YÖKSİS Yazar Kaydı

Yazar Adı ÇÖL RAMAZAN,Montgomery Alicia,Iazbik Maria Cristina,Defelice Ashley,Saavedra Paulo Vilar,Couto Guillermo
YÖKSİS ID 3740046

Metrikler

Scopus Atıf 6
Havuz Atıfları 0
Yazar Sayısı 6