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Identification and antifungal susceptibility of Candida species isolated from bloodstream infections in Konya Turkey
Annals of Clinical Microbiology and Antimicrobials 2016 Cilt 15 Sayı 1
Scopus Eşleşmesi Bulundu
47
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15
Cilt
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Özet
Background: In this study, our aim was to identify Candida species isolated from bloodstream infections and to determine their susceptibilities to various antifungal agents to demonstrate the local resistance profiles and to guide empirical treatment for clinicians. Methods: Two hundred Candida isolates (95Candida albicans, 105 non-albicans Candida strains) were included in the study. Candida species were identified by conventional, biochemical and molecular methods. Antifungal susceptibility tests for amphotericin B, fluconazole, voriconazole, posaconazole, caspofungin and anidulafungin were performed with broth microdilution method according to the Clinical and Laboratory Standards Institute M27-A3 document. Results: Of the 200 Candida strains, the most prevalent species were C. albicans (47.5%), Candida glabrata (18.0%) and Candida parapsilosis complex (14.0%). All Candida species except for three (1.5%) Candida kefyr strains were susceptible to amphotericin B. Only one (2.8%) C. glabrata was resistant to fluconazole (MIC ≥ 64 μg/ml), and the others (97.2%) exhibited dose-dependent susceptibility. All species, but C. glabrata strains, were susceptible to fluconazole. Resistance to voriconazole, posaconazole, caspofungin and anidulafungin was not detected in any strain. Conclusion:Candida albicans were susceptible to all antifungal drugs. Three C. kefyr strains were resistant to amphotericin B. Only one C. glabrata was resistant to fluconazole. All the strains were susceptible to voriconazole, posaconazole, caspofungin and anidulafungin. In vitro antifungal susceptibility tests should be performed to select of appropriate and effective antifungal therapy, and monitor the development of resistance.
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15
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Article
Belge Türü
Kaynak: ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS
Anahtar Kelimeler (WoS)

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Scimago Dergi Bilgisi Otomatik ISSN Eşleştirmesi 2016 yılı verileri
Annals of Clinical Microbiology and Antimicrobials
Q1
SJR Quartile
1,042
SJR Skoru
75
H-Index
🔓
Açık Erişim
Kategoriler: Medicine (miscellaneous) (Q1) · Infectious Diseases (Q2) · Microbiology (medical) (Q2)
Alanlar: Medicine
Ülke: United Kingdom · BioMed Central Ltd
Bu bilgiler makale yılına göre Scimago veritabanından ISSN eşleştirmesiyle otomatik getirilmektedir. Dergi sıralama verileri Scimago'nun ilgili yılı baz alınmaktadır.

Anahtar Kelimeler

WoS | Bir kelimeye tıklayıp ilgili kaynaktaki yayınları görün.

Makale Bilgileri

Dergi Annals of Clinical Microbiology and Antimicrobials
ISSN 1476-0711
Yıl 2016 / 12. ay
Cilt / Sayı 15 / 1
Makale Türü Özgün Makale
Hakemlik Hakemli
Endeks SCI-Expanded
Teşvik Puanı 12,00 · YÖKSİS Akademik Teşvik
Yayın Dili İngilizce
Kapsam Uluslararası
Toplam Yazar 4 kişi
Erişim Türü Elektronik
Alan Sağlık Bilimleri Temel Alanı- Tıbbi Mikrobiyoloji

YÖKSİS Yazar Kaydı

Yazar Adı TÜRK DAĞI HATİCE,FINDIK DUYGU,Senkeles Cigde,ARSLAN UĞUR
YÖKSİS ID 2134783

Metrikler

Scopus Atıf 47
Havuz Atıfları 0
Teşvik Puanı 12,00
Yazar Sayısı 4