Bond strength of root canal sealers to dentin is an important property for the integrity of the sealings of root-canals. The purpose of this study was to test shear bond strength of three endodontic sealers (Diaket, AH Plus and Endo-REZ). The coronal two thirds of ninety extracted human third molars were removed. The smear layer of the exposed dentin surfaces were removed using 17% EDTA followed by 5.25% NaOCl and the teeth were randomly divided into two groups (n = 45). Group 1 was kept as control and in group 2, uniform smear layer was created using waterproof polishing papers. Three-mm long sections of polyethylene tubing were filled with freshly mixed sealer and placed on the dentin surfaces for conducting a shear bond strength test. The data was calculated as MPa and was statistically analyzed using a two way ANOVA, Kruskal-Wallis and Mann-Whitney U tests. A significant difference was found among the bond strength of the sealers, smear layer, and control groups. AH Plus sealer showed the highest bond strength in smear layer removed surfaces (p < 0.05). Pretreatment with EDTA/ NaOCl affected bond strength of AH Plus. AH Plus had the highest bond to dentin with or without smear layer. Copyright © 2005 by the American Association of Endodontists.