A new species, Globularia anatolica A. Duran, O.Çetin &M. Oztiirk (Globulariaceae) is described and illustrated from southwest Turkey. The species grows on eroded gypsum slopes and in open Pinus brutia Ten. forest in the Honaz Mountain National Park (C2 Denizli province). It is closely related to G. sintenisii Hausskn. &Wettst., an endemic species confined to southwest Anatolia. Diagnostic morphological characters of Globularia anatolica are discussed and presented as a key to Turkish Globularia. It is suggested that the new species should be regarded as 'Critically Endangered' (CR) according to the IUCN criteria. In addition, the biogeography of the Honaz Mountain is briefly outlined. © Nordic Journal of Botany 2009.