In this study, we investigated the antioxidant activity of the extracts of Arum dioscoridis grown in Turkey. The antioxidant activity of the methanolic and acetone extracts from Arum dioscoridis seed was measured by various assays including ferric reducing antioxidant power, cupric reducing antioxidant capacity, scavenging activity of hydrogen peroxide and metal chelating capacity. The methanolic extract showed higher antioxidant activity with 85.4±2.1%. Fatty acid compositions of the methanolic and acetone extracts of Arum dioscoridis were analysed. Data suggested that Arum dioscoridis grown in Turkey may be importance source as natural antioxidant.