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Phenolic constituent, antioxidative and tyrosinase inhibitory activity of Ornithogalum narbonense L. from Turkey: A phytochemical study
Scopus
Toplam 116 atıf DOI
This study examined the antioxidant and anti-tyrosinase activity and phenolic profiles of three extracts (ethyl acetate, methanol and water) obtained from different anatomical parts (bulb, stem and seed) of Ornithogalum narbonense. Antioxidant activity of the extracts was evaluated using DPPH*, ABTS+*, FRAP, CUPRAC, metal chelating and phosphomolybdenum assays. Tyrosinase inhibitory activity was measured using the modified dopachrome method with l-DOPA as the substrate. Phenolic content of the extracts varied according to plant part and extraction solvent and included HPLC-DAD, epicatechin, rutin, ferulic, protocateuchic p-hydroxybenzoic, chlorogenic, caffeic, benzoic and rosmarinic acids. The ethyl acetate extract of O. narbonense bulb samples demonstrated the most antioxidant and anti-tyrosinase activity and had the highest phenolic content. All other extracts showed moderate antioxidant and anti-tyrosinase activity. O. narbonense extracts, especially ethanol extract of O. narbonense bulbs, may have dietary and medicinal applications.
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Antioxidant properties and enzyme inhibitory effects of extracts from Mandragora autumnalis and its fatty acid composition
Scopus
Havuzumuzda 16 atıf almış
The present research was performed to evaluate antioxidant activities and enzyme inhibitory potentials of two extracts (acetone and methanol) from two parts (flowers and leaves) of Mandragora autumnalis. The antioxidant properties were evaluated by using different methods. Enzyme inhibitory potentials were tested against cholinesterase (AChE and BChE), tyrosinase, α-amylase and α-glucosidase. Fatty acids, total phenolics and flavonoid content were investigated for phytochemical composition. Generally, the methanolic extract of flowers (F-Met) exhibited the strongest antioxidant effect with the highest level of phenolics. Total phenolic and flavonoid content were determined as 26.10-46.92 mgGAE/g extract and 3.60-26.11 mgRE/g extract, respectively. α-linolenic acid was found to be major fatty acids in the studied oils (33.81% for flowers and 39.15% for leaves). The study suggested that M. autumnalis could be valuable as a source of natural agents in food and pharmaceutical applications.
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Kurumlar (1)
Selçuk Üniversitesi
Selçuklu, Turkey