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Survey of phytochemical composition and biological effects of three extracts from a wild plant (Cotoneaster nummularia Fisch. et Mey.): A potential source for functional food ingredients and drug formulations
Scopus
Open Access Toplam 120 atıf DOI
This study was focused on the analysis of the phenolic content, antioxidant, antibacterial, anti-cholinesterase, anti-tyrosinase, anti-amylase and anti-glucosidase activity of three solvent extracts from Cotoneaster nummularia. Moreover, water extract was tested in terms of mutagenic/anti-mutagenic effects. The antioxidant activities of these extracts were evaluated by DPPH, ABTS, O2, metal chelating, phosphomolybdenum, b-carotene/linoleic acid, ferric and cupric reducing power assays. Enzyme inhibitory activities were also examined with colorimetric methods. Generally, methanol and water extracts exhibited excellent biological activities. These extracts were rich in phenolic and flavonoid content. Furthermore, Cotoneaster extracts indicated appreciable antibacterial properties against human pathogen strains. HPLC analysis showed that ferulic acid, chlorogenic acid, (-)-epicatechin and (+)-catechin were the major phenolics in extracts tested. These data offer that these extracts from C. nummularia may be considered as a potential source of biological agents for developing functional foods or drug formulations. Copyright:
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Natural two Taraxacum species effective against frameshift and base pair substitution mutations: Mutagenic, antimutagenic and antioxidant evaluation
Scopus
Havuzumuzda 2 atıf almış
Plant or plant products have gained increasing importance in pharmacology and food industries in recent years due to their lower toxicity and side effects. The genus Taraxacum belonging to Asteraceae family have been used in traditional medicine since ancient times. In this study, antioxidant, mutagenic and antimutagenic properties of two Taraxacum species namely T. mirabile and T. farinosum were investigated. Antioxidant properties were determined by different test systems including DPPH radical scavenging, reducing power (CUPRAC and FRAP assays) and phosphomolybdenum assays. Total phenolic and flavonoid contents were also reported. Mutagenic and anti-mutagenic activities were tested by Ames assay. It was seen that Taraxacum species have moderate antioxidant and antimutagenic activities ranging between moderate to strong. However, the species were found to be non-mutagenic. It was determined that total phenolic and flavonoid contents in T. mirabile (23.43 mgGAE/g extract and 4.58 mgRE/g extract) were higher than T. farinosum (17.54 mgGAE/g extract and 3.37 mgRE/g extract).
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Kurumlar (1)
Selçuk Üniversitesi
Selçuklu, Turkey