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Survey of phytochemical composition and biological effects of three extracts from a wild plant (Cotoneaster nummularia Fisch. et Mey.): A potential source for functional food ingredients and drug formulations
Scopus
Open Access Toplam 120 atıf DOI
This study was focused on the analysis of the phenolic content, antioxidant, antibacterial, anti-cholinesterase, anti-tyrosinase, anti-amylase and anti-glucosidase activity of three solvent extracts from Cotoneaster nummularia. Moreover, water extract was tested in terms of mutagenic/anti-mutagenic effects. The antioxidant activities of these extracts were evaluated by DPPH, ABTS, O2, metal chelating, phosphomolybdenum, b-carotene/linoleic acid, ferric and cupric reducing power assays. Enzyme inhibitory activities were also examined with colorimetric methods. Generally, methanol and water extracts exhibited excellent biological activities. These extracts were rich in phenolic and flavonoid content. Furthermore, Cotoneaster extracts indicated appreciable antibacterial properties against human pathogen strains. HPLC analysis showed that ferulic acid, chlorogenic acid, (-)-epicatechin and (+)-catechin were the major phenolics in extracts tested. These data offer that these extracts from C. nummularia may be considered as a potential source of biological agents for developing functional foods or drug formulations. Copyright:
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Phenolic compounds, antioxidant properties and enzyme inhibition ability of adiantum capillus veneris L. Linked to Alzheimer’s disease, diabetes mellitus and skin disorders
Scopus
Havuzumuzda 17 atıf almış
Adiantum capillus-veneris L. is one of the best ferns that are used in traditional medicine for breaking kidney stones. This study aimed to evaluate antioxidant activity of the different extracts of A. capillus-veneris using the phosphomolybdenum assay, free radical scavenging activity (DPPH), ferric reducing antioxidant power (FRAP), and cupric ion reducing power activity test (CUPRAC). Besides, the enzyme inhibition activities were determined against acetylcholinesterase, tyrosinase, α-glucosidase and α-amylase. Total and individual phenolic compounds were also determined by spectrophotometric and HPLC methods, respectively. Total phenolic and flavonoid contents were found to change between 354-441 mg GAE/g and 23-123 mg QE/g, respectively. The major phenolic compounds were benzoic acid, epicatechin, syringic acid and catechin. Methanol andethyl acetate extracts exhibited stronger antioxidant abilities compared to water extract. A. capillus-veneris extracts showed high enzyme inhibition activities except for butrylcholinesterase. The results indicated that the different extracts of A. capillus-veneris L. can be used as natural sources of antioxidants and enzyme inhibitors.
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Kurumlar (2)
Aksaray Üniversitesi
Aksaray, Turkey
Selçuk Üniversitesi
Selçuklu, Turkey