Kurumun Atıf Alan Makalesi
Atıf Alan Yayın
An ethnobotanical survey of inner-west Anatolia, Turkey
Scopus
Toplam 143 atıf DOI
This study is focused on ethnobotanical usages of wild plants growing within the Afyonkarahisar province districts of Sinanpaia, Hocalar and Dazkiri. Ninety local informants in 11 villages were interviewed. A total of 129 different usages of wild plants in the study area were recorded. Out of 650 plant species commonly present, 93 plant taxa (14.3%) belonging to 43 families were used for medicinal (52 citations), foodstuff (37 citations), fodder (14 citations), dye (six citations), firewood (five citations), construction materials (four citations) and miscellaneous purposes (11 citations). At least 15% of the information regarding ethnobotanical uses of wild plants was obtained by showing herbarium voucher samples to the informants. It was noted that Sideritis leptoclada and Verbascum stenostachyum are endemic to Turkey and their endangered status has markedly increased in recent years because of increased collecting for ethnobotanical purposes. Informants indicate that members of the younger generation have a much reduced interest in ethnobotanical knowledge and that this is a danger to the continued use of local plants. © Springer Science+Business Media, LLC 2008.
Atıf Kaynağı
Atıf Yapan Yayın
Chemical profiling and pharmaco-toxicological activity of Origanum sipyleum extracts: Exploring for novel sources for potential therapeutic agents
Scopus
Havuzumuzda 25 atıf almış
The phytochemical, antiradical, and enzyme inhibition profile of three solvent extracts (ethyl acetate, methanol, water) of Origanum sipyleum were assessed. We also performed a pharmacological study in order to explore protective effects induced by extracts in inflamed colon. LC-MS analysis revealed that the extracts contained different classes of phenolics. The aqueous extract showed the highest antioxidant and acetylcholinesterase (AChE) inhibitory effects. Total phenol and flavonoid contents were highest in aqueous and ethyl acetate extract, respectively. All extracts were effective in reducing colon pro-oxidant and pro-inflammatory biomarkers. The extracts revealed also able to inhibit fungal and bacterial species involved in ulcerative colitis, including Candida albicans, Candida tropicalis, Staphylococcus aureus, and Staphylococcus thyphimurium. Finally, we also showed the antiproliferative effects exerted by the EA extracts on human colon cancer HCT116 cell line. Concluding, our results indicated that O. sipyleum extracts displayed promising therapeutic properties which warrants further validation. Practical applications: The present phytochemical and biological studies, including antioxidant, anti-inflammatory, and antimicrobic assessments, showed significant protective effects exerted by O. sipyleum extracts in an experimental model of ulcerative colitis. The results are intriguing and suggest potential applications O. sipyleum extracts as sources of natural agents for the management of clinical symptoms related to ulcerative colitis, characterized by increased burden of oxidative stress and microbiome dysbiosis.
Atıf Yapan Makale Bilgileri
Kurumlar (6)
Medical University of Sofia
Sofia, Bulgaria
Selçuk Üniversitesi
Selçuklu, Turkey
Università degli Studi di Perugia
Perugia, Italy
Università degli Studi di Urbino Carlo Bo
Urbino, Italy
University of G. d'Annunzio Chieti and Pescara
Chieti, Italy
University of Mauritius
Reduit, Mauritius