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Effect of clinoptilolite on serum biochemical and haematological characters of broiler chickens during aflatoxicosis
Scopus
Toplam 144 atıf DOI
Clinoptilolite (CLI, a natural zeolite) incorporated into the diet at 1.5 and 2.5 per cent were evaluated for their ability to reduce the deleterious effects of 2.5 mg total aflatoxin (AF) kg-1 diet on broiler chickens from 1 to 21 days of age. In total 360 broiler chicks were divided into six equal treatment groups (control, AF, CLI (1.5 per cent), AF plus CLI (1.5 per cent), CLI (2.5 per cent) and AF plus CLI (2.5 per cent)). When compared with the controls, AF treatment significantly decreased serum total protein, albumin, inorganic phosphorus, uric acid, total cholesterol and the values of haematocrit, red blood cell counts, mean corpuscular volume, haemoglobin, thrombocyte counts, percentage of monocyte counts; increased values of white blood cell and heterophil counts. The addition of CLI (1.5 per cent) and CLI (2.5 per cent) to the AF-containing diet reduced the adverse effects of AF and should be helpful in a solution to the aflatoxicosis problem in poultry. (C) 2000 Harcourt Publishers Ltd.
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Effects of aflatoxin on the proportions of peripheral blood leukocytes and alpha-naphtyl acetate esterase (ANAE) positive lymphocytes in the mouse
Scopus
Havuzumuzda 9 atıf almış
In this study detrimental effects of aflatoxin (AF) on the peripheral blood formula and the alpha naphthyl acetate esterase (ANAE) - positivity profile of peripheral blood lymphocytes (PBL) on the mice were determined. A total of 40 white mice were randomly divided in to 5 groups each having 8 animals. The first group served as a control and received standard diet. The remaining 4 groups were fed diets containing 200, 400, 800 and 1600 ppb AF, respectively. The results of this study have revealed that AF given by the food caused significant declines both in the proportion of PBL and in the percentages of ANAE-positive peripheral blood lymphocytes (T-lymphocytes) in a dose dependent manner. These results may be concerned as a haematological evidence for immuno-suppressive effect of AF on cell-mediated immunity.
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Kurumlar (2)
Selçuk Üniversitesi
Selçuklu, Turkey
Veterinary Control and Research Institute
Adana, Turkey