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Functional constituents of wild and cultivated Goji (L. barbarum L.) leaves: phytochemical characterization, biological profile, and computational studies
Scopus
Open Access Toplam 182 atıf DOI
Goji (Lycium barbarum L.) leaves are emphasized as a functional tea or as dietary supplements. The phenolic compound profile, antioxidant, enzyme inhibitory, antimicrobial, and antimutagenic activities of leaf extracts from two selected cultivars in comparison with wild-growing plants have been evaluated. HPLC-DAD/ESI-ToF-MS analysis revealed the presence of phenolic acids and flavonoids with chlorogenic acid and rutin being the dominant compounds in the cultivated plants, whereas rutin and kaempeferol-3-O-rutinoside for wild growing ones. In particular, cv. Erma contained the highest amount of chlorogenic acid and showed a strong tyrosinase-inhibitory effect. Staphylococcus aureus, Listeria monocytogenes, and Penicillium funiculosum were the most sensitive strains when exposed to extracts from cultivated plants. Antimutagenic activity was evaluated by Ames' test. The tested extracts provided high protection against mutagenicity induced by 2-anthramine (2-AA) to Salmonella typhimurium strains TA 98 and TA 100 (max. inhibition (%) 88% and 74.2%, respectively). Overall, Goji leaves are a rich source of bioactive compounds with functional properties that need further risk/benefit evaluation when used in foods or health-promoting formulations.
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Influence of drying process on chemical composition, antioxidant and enzyme-inhibitory activity of Helichrysum italicum essential oils
Scopus
Havuzumuzda 8 atıf almış
Introduction: Helichrysum italicum (Roth) G. Don, also known as immortelle, is a medicinal plant from the Mediterranean region. It is widely used in traditional medicine as an antiinflammatory and antimicrobial agent. Owing to the rich composition and beneficial effects of its essential oil, it is not only attractive for use in traditional medicine but also in pharmacy, medicine, and cosmetology. This study examines the chemical composition and biological activity of the essential oil obtained from fresh and dried immortelle, as well as the influence of the drying technique on the oil's quality. Methods: To isolate the essential oil from immortelle, fresh, naturally dried, and freeze-dried aerial parts of the plant were subjected to the hydrodistillation. The essential oils obtained were then characterized chemically and biologically. Results: GC-MS analysis showed that α-pinene (29.77%) was the dominant compound in the oil isolated from the fresh plant, while α-muurolene was the most abundant compound in samples obtained from dried plants (ranging from 30.03% to 20.15%). The essential oil isolated from the fresh plant exhibited the highest antioxidant activity, whereas the oil obtained from freeze-dried plants showed the lowest potential. In terms of amylase inhibition, similar activity was observed, while the situation was opposite for tyrosinase inhibition. Conclusion: This research provides a detailed insight into the influence of the drying technique on the chemical composition and biological activity of immortelle essential oil. The study demonstrates the potential of using immortelle essential oil as a natural agent for diabetes and hyperpigmentation control.
Atıf Yapan Makale Bilgileri
Kurumlar (3)
Institute of General and Physical Chemistry Serbia
Belgrade, Serbia
Selçuk Üniversitesi
Selçuklu, Turkey
University of Novi Sad
Novi Sad, Serbia