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INVESTIGATION OF ANTIOXIDANT POTENTIALS OF SOLVENT EXTRACTS FROM DIFFERENT ANATOMICAL PARTS OF ASPHODELINE ANATOLICA E. TUZLACİ: AN ENDEMIC PLANT TO TURKEY
African Journal of Traditional Complementary and Alternative Medicines Cilt 11 ss. 481-488
Scopus Open Access Toplam 186 atıf DOI
Background: The genus Asphodeline (Liliaceae) is represented in Turkey by 20 taxa, which are traditionally used for medicinal purposes in Anatolia. Materials and Methods: In this study, we tested the phytochemical content and antioxidant effect of different solvent extracts obtained from different anatomical parts of Asphodeline anatolica. The different extracts of each plant parts were tested for antioxidant activity using different chemical assays. The total antioxidant components were also calculated. Results: Generally, acetone extracts produced the seed and root exhibited significantly higher antioxidant activity with high antioxidant components. Total phenolic content of extracts were significantly correlated with antioxidant potentials (except for, metal chelating activity). Conclusion: On the basis of the results obtained, A. anatolica extracts should be regarded as a valuable source of natural antioxidants for food and therapeutic applications.
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Multicomponent pattern and biological activities of seven Asphodeline taxa: Potential sources of natural-functional ingredients for bioactive formulations
Journal of Enzyme Inhibition and Medicinal Chemistry Cilt 32 ss. 60-67
Scopus Havuzumuzda Open Access 73 atıf almış
The current study was carried out to evaluate multicomponent pattern, biological and enzymatic activities of seven Asphodeline taxa root extracts as useful ingredients, due to the fact that these plants are commonly used as traditional food supplements in Turkish regions. The extracts were characterized for free anthraquinones and phenolics to obtain a specific chemical fingerprint useful for quality control. These analyzes were coupled to biological and enzymatic activities in order to obtain comprehensive information of the natural product. Free anthraquinones and phenolics were determined using validated HPLC-PDA methods. Antioxidant properties were determined by different procedures including free radical scavenging, reducing power, phosphomolybdenum and metal chelating assays. Ames assay was performed to evaluate mutagenic/antimutagenic properties. Enzyme inhibitory activities were tested against cholinesterase, tyrosinase, a-amylase and a-glucosidase. From the herein reported results, Asphodeline could be valuable for the production of bioactive products or food supplements for cosmetic and pharmaceutical industries. List of abbreviations: ABTS: 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); AChE: acetylcholinesterase; ADD: A. damascena subsp. damascena; ADG: A. damascena subsp. gigantea; ADO: A. damascena subsp. ovoidea; ADR: A. damascena subsp. rugosa; APR: A. prismatocarpa; ATT: A. tenuior subsp. tenuiflora var. tenuiflora; ATU: A. turcica; BChE: butyrylcholinesterase; CUPRAC: cupric ion reducing; DPPH: 2,2-diphenyl-1-picrylhydrazyl; en: endemic; FDA: Food and Drug Administration; FRAP: ferric ion reducing antioxidant power; GAE: gallic acid equivalents; HPLC-PDA: high performance liquid chromatography - photodiode array detector; RE: rutin equivalents; TE: trolox equivalents.
Atıf Yapan Makale Bilgileri
Kurumlar (4)
Interuniversity Consortium of Structural and Systems Biology Rome, Italy
Medical University of Sofia Sofia, Bulgaria
Selçuk Üniversitesi Selçuklu, Turkey
University of G. d'Annunzio Chieti and Pescara Chieti, Italy