Kurumun Atıf Alan Makalesi
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Composition, antioxidant, antimicrobial and enzyme inhibition activities of two Origanum vulgare subspecies (subsp. vulgare and subsp. hirtum) essential oils
Scopus
Toplam 224 atıf DOI
Essential oils (EOs) from Origanum vulgare subsp. vulgare (OVV) and O. vulgare subsp. hirtum (OVH) were evaluated for antioxidant activities (DPPH, ABTS, FRAP, CUPRAC, β-carotene/linoleic acid, phosphomolybdenum and metal chelating), antimicrobial and inhibitory properties against acetylcholinesterase, butrylcholinesterase, tyrosinase, α-amylase and α-glucosidase. Thymol and linalool were identified as major component in OVV and OVH essential oils, respectively. O. vulgare subsp. vulgare exhibited a strong free radical scavenging, reducing power, antimicrobial and acetylcholinesterase, butrylcholinesterase, α-amylase and α-glucosidase inhibitory activity. Interestingly, OVH possess a significant metal chelating and tyrosinase inhibitory activities. The EOs of both species exhibited moderate antibacterial and antifungal activities. The MIC values of the EOs ranged from 85.3 to 426.7. μg/mL. O. vulgare subsp. vulgare showed higher activity against Sarcina lutea with the lowest MIC (85.3. μg/mL), whereas OVH indicated strong activity for Candida albicans with MIC value of 85.3. μg/mL. The data suggest that the Origanum EOs could be used as valuable new natural agents with functional properties for food and pharmacology industries.
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Atıf Yapan Yayın
Chemodiversity and biological activity of essential oils from three species from the Euphorbia genus
Scopus
Havuzumuzda 19 atıf almış
Several studies demonstrated the wide pharmacological properties of extracts and essential oils (EOs) prepared from Euphorbia species. In the present study, the chemical composition and biological activities of EOs from three different Euphorbia species were evaluated using in vitro methods. A total of 29, 33 and 42 constituents were identified in the EOs of E hirta, E convolvuloides and E heterophylla, respectively. The EOs exhibited in vitro radical scavenging potential in the ABTS assay (2.89-21.50 mg/g). Additionally, an inhibitory effect on acetylcholinesterase (4.23-5.12 mg/g) was detected. Besides, remarkable tyrosinase inhibition was reported by the EOs (95.24-113.74 mg/g). Molecular docking was also performed to elucidate the binding interactions between selected EO components and enzymes. Phytol and geranyl-(E)-acetone had a good binding with tyrosinase in the molecular docking. This study highlighted the promising pharmacological profiles of these EOs as natural sources of antioxidants as well as cholinesterase and tyrosinase inhibitors that could be further explored in the management of human ailments in food and pharmaceutical industries.
Atıf Yapan Makale Bilgileri
Kurumlar (6)
Selçuk Üniversitesi
Selçuklu, Turkey
Università Cattolica del Sacro Cuore, Campus di Piacenza e Cremona
Piacenza, Italy
Università degli Studi di Perugia
Perugia, Italy
Université Félix Houphouët-Boigny
Abidjan, Cote d'Ivoire
University of G. d'Annunzio Chieti and Pescara
Chieti, Italy
University of Mauritius
Reduit, Mauritius