Kurumun Atıf Alan Makalesi
Atıf Alan Yayın
Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. species
Scopus
Toplam 223 atıf DOI
The methanol and aqueous extracts of three endemic Centaurea species (C. polypodiifolia var pseudobehen, C. pyrrhoblephara and C. antalyense) were investigated for their antioxidant and cholinesterase inhibitory activities. The antioxidant activities of these extracts were evaluated by in vitro models including, phosphomolybdenum assay, free radical scavenging assays (DPPH and ABTS), β-carotene/linoleic acid test system, metal chelating assay, FRAP assay, ferric and cupric reducing power. Cholinesterase inhibitory activities were examined using Ellman's colorimetric method. Total phenol, flavonoid, and saponin contents were also measured. Among the six Centaurea extracts evaluated, the highest antioxidant abilities were obtained from C. polypodiifolia var pseudobehen. Methanolic extracts from C. polypodiifolia var pseudobehen and C. antalyense had a noticeable inhibition towards AChE and BChE. These findings suggest that Centaurea species could be an anticholinesterase agent and antioxidant resource in some industries, such as food, pharmacology, and cosmetics. © 2013 Elsevier Ltd.
Atıf Kaynağı
Atıf Yapan Yayın
HPLC-DAD analysis of phenolic compounds and antioxidant properties of Asphodeline lutea roots from Bulgaria and Turkey
Scopus
Havuzumuzda 34 atıf almış
Asphodeline lutea (L.) Rchb. is a wild edible plant, traditionally consumed in the Mediterranean diet, but there are limited literature data about its medicinal properties. Methanol extracts of A. lutea roots from Bulgarian (ALB) and Turkish (ALT) origin were evaluated for their antioxidant activity using various in vitro models: phosphomolybdenum assay, free radical scavenging activity, metal chelating activity and ferric and cupric reducing power. Both methanolic extracts were analyzed for phenolic derivatives by HPLC-DAD. Caffeic acid was the dominant phenolic acid being present up to 2.19. ±. 0.020. mg/g extract in ALB. The highest content of (+) catechin (1.54. ±. 0.060. mg/g) and (-) epicatechin (3.18. ±. 0.160. mg/g) was found in ALB as well as total polyphenolics (22.45. ±. 0.95. mg/g GAEs/g extract). The ALT revealed the highest total flavonoid content (34.99. ±. 0.39. mg REs/g extract). Free radical scavenging activity of ALB against DPPH (25.39. ±. 0.36. mg TEs/g extract) and ABTS (33.99. ±. 1.06. mg TEs/g) was evaluated. In addition, ALB had stronger metal chelating activity (7.31. ±. 0.31. mg EDTAEs/g extract) and higher ferric (34.67. ±. 0.51. mg TEs/g extract) and cupric (23.82. ±. 0.36. mg TEs/g) reduction ability as compared with the ALT. Total antioxidant capacity of ALB in phosphomolybdenum test was assayed (236.80. ±. 0.86. mg AEs/g extract). A. lutea roots have a significant potential in safeguarding against various induced oxidative stress. © 2014 Elsevier B.V.
Atıf Yapan Makale Bilgileri
Kurumlar (2)
Medical University of Sofia
Sofia, Bulgaria
Selçuk Üniversitesi
Selçuklu, Turkey