Kurumun Atıf Alan Makalesi
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Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. species
Scopus
Toplam 223 atıf DOI
The methanol and aqueous extracts of three endemic Centaurea species (C. polypodiifolia var pseudobehen, C. pyrrhoblephara and C. antalyense) were investigated for their antioxidant and cholinesterase inhibitory activities. The antioxidant activities of these extracts were evaluated by in vitro models including, phosphomolybdenum assay, free radical scavenging assays (DPPH and ABTS), β-carotene/linoleic acid test system, metal chelating assay, FRAP assay, ferric and cupric reducing power. Cholinesterase inhibitory activities were examined using Ellman's colorimetric method. Total phenol, flavonoid, and saponin contents were also measured. Among the six Centaurea extracts evaluated, the highest antioxidant abilities were obtained from C. polypodiifolia var pseudobehen. Methanolic extracts from C. polypodiifolia var pseudobehen and C. antalyense had a noticeable inhibition towards AChE and BChE. These findings suggest that Centaurea species could be an anticholinesterase agent and antioxidant resource in some industries, such as food, pharmacology, and cosmetics. © 2013 Elsevier Ltd.
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Atıf Yapan Yayın
Functional components, antidiabetic, anti-Alzheimer’s disease, and antioxidant activities of Salvia syriaca L.
Scopus
Havuzumuzda Open Access 84 atıf almış
Antidiabetic, anti-Alzheimer, general toxicity, and antioxidant activities of Salvia syriaca were evaluated. Phytochemical composition of the essential oil and methanolic extract of the plant were identified using gas chromatography-mass spectrometry and reverse-phase high-performance liquid chromatography-diode array detector techniques, respectively. Essential oil of S. syriaca exhibited strong cytotoxicity, antioxidant, α-amylase, and α-glucosidase inhibitory activities. Gas chromatography-mass spectrometry analysis showed that spathulenol (87.4%), isospathulenol (7.6%), and bornyl acetate (2.7%) are the major compounds in essential oil. High-performance liquid chromatography analysis indicated that rutin, quercetin, apigenin, rosmarinic acid, and ferulic acid are the most abundant phenolic components. S. syriaca could be considered as a valuable source of bioactive natural compounds for functional foods, medical, and pharmaceutical applications.
Atıf Yapan Makale Bilgileri
Kurumlar (6)
Biotechnology Research Center,Tabriz
Tabriz, Iran
Imam Khomeini International University
Qazvin, Iran
Research Center for Pharmaceutical Nanotechnology
Tabriz, Iran
Selçuk Üniversitesi
Selçuklu, Turkey
Süleyman Demirel Üniversitesi
Isparta, Turkey
Urmia University of Medical Sciences
Urmia, Iran