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Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. species
Scopus
Toplam 223 atıf DOI
The methanol and aqueous extracts of three endemic Centaurea species (C. polypodiifolia var pseudobehen, C. pyrrhoblephara and C. antalyense) were investigated for their antioxidant and cholinesterase inhibitory activities. The antioxidant activities of these extracts were evaluated by in vitro models including, phosphomolybdenum assay, free radical scavenging assays (DPPH and ABTS), β-carotene/linoleic acid test system, metal chelating assay, FRAP assay, ferric and cupric reducing power. Cholinesterase inhibitory activities were examined using Ellman's colorimetric method. Total phenol, flavonoid, and saponin contents were also measured. Among the six Centaurea extracts evaluated, the highest antioxidant abilities were obtained from C. polypodiifolia var pseudobehen. Methanolic extracts from C. polypodiifolia var pseudobehen and C. antalyense had a noticeable inhibition towards AChE and BChE. These findings suggest that Centaurea species could be an anticholinesterase agent and antioxidant resource in some industries, such as food, pharmacology, and cosmetics. © 2013 Elsevier Ltd.
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Effects of extraction and drying techniques on the chemical composition and biological activities of Helichrysum italicum
Scopus
Havuzumuzda 20 atıf almış
In this study, the impact of different drying processes, conventional air-drying (S) and freeze drying (F), on biochemical composition and biological activity of extracts of Helichrysum italicum obtained by using traditional (maceration- MAC) and modern extraction techniques (ultrasound (UAE) and microwave (MAE) extraction) was screened. The total phenol content of examined extracts yield in range of 49.7–119.77 mg GAE/g, while total flavonoid content yield in range of 2.92–21.96 mg RE/g. Qualitative and quantitative analysis showed that rutin and quercetin are the components that are present in all extracts in high amount. Radical scavenging activity was confirmed by DPPH and ABTS tests, and reduction ability by FRAP and CUPRAC tests. Total antioxidant activity and chelating ability of the extracts were also confirmed. While ethanol extracts (E) exhibited higher anti-acetylcholinesterase, water extracts (W) were more active in butyrylcholinesterase enzyme inhibition. All extracts were found to inhibit tyrosinase, amylase and glucosidase enzymes. Microwave extraction technique was found to be better extraction technique and air-drying more effective drying process for isolation of phenolic compounds and biological activity of Helichrysum italicum.
Atıf Yapan Makale Bilgileri
Kurumlar (3)
Selçuk Üniversitesi
Selçuklu, Turkey
University of Kragujevac
Kragujevac, Serbia
University of Novi Sad
Novi Sad, Serbia