Kurumun Atıf Alan Makalesi
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In vitro enzyme inhibitory properties, antioxidant activities, and phytochemical profile of Potentilla thuringiaca
Scopus
Toplam 432 atıf DOI
The genus Potentilla is interesting for the pharmaceutical field due to its valuable medicinal properties, which have been observed in complementary and alternative medicine. In recent years, studies conducted to estimate the biological activity of several of the Potentilla species have shown a wide spectrum of therapeutic properties. In particular, in the present paper, different extracts obtained from the herb P. thuringiaca were analysed for antioxidant and enzyme inhibitory activities. The UHPLC-DAD-MS3 hyphenated techniques reported herein allow for the identification of phytoconstituents. The analyses showed the presence of flavonoids and ellagitannins as major components. Furthermore, the data demonstrated that the analysed extracts revealed a high total antioxidant capacity in the phosphomolybdenum assay. The free radical scavenging activity of the extracts was evaluated using DPPH and ABTS assays. The reducing power activity of P. thuringiaca was also determined by FRAP and CUPRAC assays, as well as metal chelating activity. In addition, the total extracts and the different fractions of P. thuringiaca revealed potent inhibitory activities against α-amylase and α-glucosidase, AChE, tyrosinase and lipase. Surprisingly, no activity against BChE was shown. P. thuringiaca could be a valuable natural source of antioxidants with interesting inhibitory actions against the key enzymes involved in several human diseases, and could represent a valid starting point for the development of new treatment and management strategies, including its use as a food supplement.
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Evaluating Total Phenolic Content, Antioxidant Activity, High Molecular Weight Glutenin Subunits (HMW-GS), and Grain Yield Parameters of Cultivated Wheat and Hybrids
Scopus
Havuzumuzda 2 atıf almış
This study was conducted to assess the high molecular weight glutenin subunits (HMW-GS), yield, total phenolic content (TPC), and antioxidant capacity using five assays: free radical scavenging (DPPH and ABTS), reducing power (CUPRAC and FRAP), and phosphomolybdenum. Wheat species, old cultivar, landrace, and hybrid wheat genotypes were compared with adaptive modern bread and durum wheat cultivars. Under rainfed conditions, high grain yield was particularly obtained from T. turanicum, T. polonicum, and T. compactum wheat species, as T. spelta, T. compactum, T. turanicum, T. turgidum, and T. polonicum were better performed to grain yield under irrigated conditions. In the study, the wheat genotypes, T. petropavlovskyi, T. spelta, T. sphaerococcum, T. compactum, Yektay 406, Ak 702, Köse 220/39, and wheat hybrids were found to have the HMW-GS 2 + 12 in Glu-D1 in relation to low quality. The Yellowstone wheat cultivar carried high-quality alleles together for 1 in Glu-A1 and 5 + 10 in Glu-D1. The study exhibited that T. monococcum (einkorn), T. spelta (spelt), T. dicoccum (emmer), and Yektay 406 (old cultivar) for better antioxidant capacity were displayed together in the same cluster of the dendrogram constructed by DPPH, ABTS, CUPRAC, FRAP, and phosphomolybdenum assay results. In addition, significant correlations were observed between TPC, ABTS, CUPRAC, FRAP, and phosphomolybdenum. The study suggested that ancient wheat species superior to the investigated characteristics had antioxidants beneficial for healthy nutrition and may also be used in the improvement of cultivars with high yield and quality.
Atıf Yapan Makale Bilgileri
Kurumlar (2)
Selçuk Üniversitesi
Selçuklu, Turkey
Transitional Zone Agricultural Research Institute
Eskisehir, Turkey